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VASCULAR ENDOTHELIAL GROWTH FACTOR-C
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DeCS
Descriptor
English
:
Vascular Endothelial Growth Factor C
Descriptor
Spanish
:
Factor C de Crecimiento Endotelial Vascular
Descriptor
Portuguese
:
Fator C de Crescimento do Endotélio Vascular
Synonyms
English
:
VEGF-C
Vascular Endothelial Growth Factor-C
Tree Number:
D12.644.276.100.800.400
D12.776.467.100.800.400
D23.529.100.800.400
Definition
English
:
A vascular endothelial
growth
factor that specifically binds to
VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2
and
VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3
. In addition to being an angiogenic factor it can act on
LYMPHATIC VESSELS
to stimulate
LYMPHANGIOGENESIS
. It is
similar
in structure to
VASCULAR ENDOTHELIAL GROWTH FACTOR D
in that they both contain N- and C-terminal extensions that were not found in other VEGF
family
members.
History Note
English
:
2004; use VASCULAR ENDOTHELIAL GROWTH FACTOR C (NM) 1996-2003
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
38246
Unique Identifier:
D042582
Occurrence in VHL
:
Similar:
DeCS